Therapeutic Contraindications in Exotic Pets

Abstract

The selection and dosing of medications for exotic pets are often challenging because most drugs are used in an extralabel manner without pharmacokinetic and pharmacodynamic studies. Doses are often extrapolated from common domestic animals and safety data are often lacking in exotic species. Just as the bioavailability and therapeutic levels are different for each species, what may be a safe and commonly used medication in one species can be deadly in another. Various drugs with documented contraindications in certain exotic pet species are outlined in this review and the pathophysiology, clinical signs, and treatment options are described when applicable.

Keywords: Antibiotic-associated dysbiosis; Benzimidazoles; Fipronil; Glucocorticoids; Ibuprofen; Ivermectin; Ketoprofen.