Metabolic Profiling: Status, Challenges, and Perspective

Helen G Gika; Georgios A Theodoridis; Ian D Wilson

doi:10.1007/978-1-4939-7643-0_1

Metabolic Profiling: Status, Challenges, and Perspective

Methods Mol Biol. 2018:1738:3-13. doi: 10.1007/978-1-4939-7643-0_1.

Authors

Helen G Gika¹, Georgios A Theodoridis², Ian D Wilson³

Affiliations

¹ School of Medicine, Aristotle University, Thessaloniki, Greece. gkikae@auth.gr.
² Department of Chemistry, Aristotle University, Thessaloniki, Greece.
³ Department of Surgery and Cancer, Imperial College London, London, UK.

PMID: 29654579
DOI: 10.1007/978-1-4939-7643-0_1

Abstract

Metabolic profiling has advanced greatly in the past decade and evolved from the status of a research topic of a small number of highly specialized laboratories to the status of a major field applied by several hundreds of laboratories, numerous national centers, and core facilities. The present chapter provides our view on the status of the remaining challenges and a perspective of this fascinating research area.

Keywords: Biochemical pathway; Biomarker; MetID; Metabolite identification; Metabolomics; Metabonomics.

MeSH terms

Animals
Biomarkers / analysis
Chromatography, Liquid / methods*
Humans
Mass Spectrometry / methods*
Metabolomics / methods*

Substances

Biomarkers