Abstract
Twenty-five patients with cellulitis or other soft tissue infections were treated with once daily teicoplanin. One patient was withdrawn from the study because of a protocol violation but 27 of the 29 assessable infections in the other 24 patients were clinically cured or improved. Eighteen of the 20 original Gram-positive bacterial isolates (11 Staphylococcus aureus and nine beta-haemolytic streptococcus strains) were completely eradicated. No severe adverse reactions were seen but a rise in the plasma platelet count was noted in the majority of the patients during teicoplanin administration.
MeSH terms
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Adolescent
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Adult
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Aged
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Anti-Bacterial Agents / adverse effects
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Anti-Bacterial Agents / pharmacokinetics
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Anti-Bacterial Agents / therapeutic use*
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Bacterial Infections / drug therapy*
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Bacterial Infections / microbiology
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Cellulitis / drug therapy*
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Cellulitis / microbiology
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Female
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Glycopeptides / adverse effects
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Glycopeptides / pharmacokinetics
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Glycopeptides / therapeutic use
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Humans
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Male
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Middle Aged
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Skin Diseases, Infectious / drug therapy*
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Skin Diseases, Infectious / microbiology
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Staphylococcal Infections / drug therapy
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Streptococcal Infections / drug therapy
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Teicoplanin
Substances
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Anti-Bacterial Agents
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Glycopeptides
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Teicoplanin