Tissue classification and segmentation of pressure injuries using convolutional neural networks

Comput Methods Programs Biomed. 2018 Jun:159:51-58. doi: 10.1016/j.cmpb.2018.02.018. Epub 2018 Mar 3.

Abstract

Background and objectives: This paper presents a new approach for automatic tissue classification in pressure injuries. These wounds are localized skin damages which need frequent diagnosis and treatment. Therefore, a reliable and accurate systems for segmentation and tissue type identification are needed in order to achieve better treatment results.

Methods: Our proposed system is based on a Convolutional Neural Network (CNN) devoted to performing optimized segmentation of the different tissue types present in pressure injuries (granulation, slough, and necrotic tissues). A preprocessing step removes the flash light and creates a set of 5x5 sub-images which are used as input for the CNN network. The network output will classify every sub-image of the validation set into one of the three classes studied.

Results: The metrics used to evaluate our approach show an overall average classification accuracy of 92.01%, an average total weighted Dice Similarity Coefficient of 91.38%, and an average precision per class of 97.31% for granulation tissue, 96.59% for necrotic tissue, and 77.90% for slough tissue.

Conclusions: Our system has been proven to make recognition of complicated structures in biomedical images feasible.

Keywords: Convolutional neural networks; Deep learning; Image segmentation; Pressure injuries; Tissue type classification.

MeSH terms

  • Algorithms
  • Databases, Factual
  • Humans
  • Image Processing, Computer-Assisted
  • Models, Anatomic
  • Models, Statistical
  • Necrosis
  • Neural Networks, Computer*
  • Pressure Ulcer / diagnostic imaging*
  • Reproducibility of Results
  • Sensitivity and Specificity
  • Tomography, X-Ray Computed
  • Wound Healing
  • Wounds and Injuries / diagnostic imaging*