Endoscopic Approaches to Upper Tract Urothelial Carcinoma

Firas G Petros; Roger Li; Surena F Matin

doi:10.1016/j.ucl.2017.12.009

Endoscopic Approaches to Upper Tract Urothelial Carcinoma

Urol Clin North Am. 2018 May;45(2):267-286. doi: 10.1016/j.ucl.2017.12.009. Epub 2018 Feb 21.

Authors

Firas G Petros¹, Roger Li¹, Surena F Matin²

Affiliations

¹ Department of Urology, UT MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA.
² Department of Urology, UT MD Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA. Electronic address: surmatin@mdanderson.org.

PMID: 29650142
DOI: 10.1016/j.ucl.2017.12.009

Abstract

A select group of patients with upper tract urothelial carcinoma (UTUC) may meet indications for endoscopic management. Strategies for disease management are provided, based on a comprehensive review of the data using PubMed and Medline databases and marrying this with our experience with endoscopic management of UTUC. Endoscopic management of UTUC via retrograde or antegrade approaches is a viable treatment option for appropriately selected patients with low-risk UTUC, including those with low-grade, low-volume, and solitary tumors. However, recurrence risk limits these procedures to compliant patients under a vigilant surveillance program. Efficacious adjuvant therapies are needed to reduce local recurrences.

Keywords: Endoscopy; Laser; Upper-tract urothelial carcinoma; Ureteral cancer; Ureteroscopy.

Publication types

Review

MeSH terms

Carcinoma, Transitional Cell / diagnosis
Carcinoma, Transitional Cell / surgery*
Endoscopy / methods*
Humans
Kidney Neoplasms / surgery*
Ureteral Neoplasms / diagnosis
Ureteral Neoplasms / surgery*
Ureteroscopy