Nipah Virus Infection

J Clin Microbiol. 2018 May 25;56(6):e01875-17. doi: 10.1128/JCM.01875-17. Print 2018 Jun.

Abstract

Nipah virus, a paramyxovirus related to Hendra virus, first emerged in Malaysia in 1998. Clinical presentation ranges from asymptomatic infection to fatal encephalitis. Malaysia has had no more cases since 1999, but outbreaks continue to occur in Bangladesh and India. In the Malaysia-Singapore outbreak, transmission occurred primarily through contact with pigs, whereas in Bangladesh and India, it is associated with ingestion of contaminated date palm sap and human-to-human transmission. Bats are the main reservoir for this virus, which can cause disease in humans and animals. There are currently no effective therapeutics, and supportive care and prevention are the mainstays of management.

Keywords: Nipah; encephalitis; outbreaks.

Publication types

  • Historical Article
  • Review

MeSH terms

  • Abattoirs
  • Animals
  • Bangladesh / epidemiology
  • Chiroptera / virology
  • Disease Outbreaks
  • Disease Reservoirs / virology*
  • Encephalitis / epidemiology
  • Encephalitis / virology
  • Henipavirus Infections / epidemiology*
  • Henipavirus Infections / history
  • Henipavirus Infections / transmission*
  • History, 20th Century
  • History, 21st Century
  • Humans
  • India / epidemiology
  • Malaysia / epidemiology
  • Nipah Virus / genetics
  • Phoeniceae / virology
  • Singapore / epidemiology
  • Swine / virology