Clinical Management of Osteoporotic Fractures

Curr Osteoporos Rep. 2018 Jun;16(3):299-311. doi: 10.1007/s11914-018-0443-y.

Abstract

Purpose of review: This review examines recent literature regarding the clinical management of fragility fractures, provides insight into new practice patterns, and discusses controversies in current management.

Recent findings: There are declining rates of osteoporosis management following initial fragility fracture. Management of osteoporotic fractures via a multidisciplinary team reduces secondary fracture incidence and improves overall osteoporotic care. Anabolic agents (abaloparatide and teriparatide) are effective adjuvants to fracture repair, and have shown positive results in cases of re-fracture in spite of medical management (i.e., bisphosphonates). For AO 31-A1 and A2 intertrochanteric hip fractures (non-reverse obliquity), no clinical advantage of intramedullary fixation over the sliding hip screw (SHS) has been proven; SHS is more cost-effective. As fragility fracture incidence continues to rise, orthopedic surgeons must play a more central role in the care of osteoporotic patients. Initiation of pharmacologic intervention is key to preventing subsequent fragility fractures, and may play a supportive role in initial fracture healing. While the media bombards patients with complications of medical therapy (atypical femur fractures, osteonecrosis of jaw, myocardial infarction), providers need to understand and communicate the low incidence of these complications compared with consequences of not initiating medical therapy.

Keywords: Bisphosphonates; Bone mineral density; Fracture management; Fragility; Hip fracture; Osteoporosis.

Publication types

  • Review

MeSH terms

  • Bone Density Conservation Agents / therapeutic use*
  • Bone Screws
  • Diphosphonates / therapeutic use
  • Fracture Fixation / methods
  • Fracture Fixation, Intramedullary / methods*
  • Fracture Healing*
  • Hip Fractures / therapy*
  • Humans
  • Osteoporotic Fractures / therapy*
  • Parathyroid Hormone-Related Protein / therapeutic use
  • Recurrence
  • Secondary Prevention
  • Teriparatide / therapeutic use

Substances

  • Bone Density Conservation Agents
  • Diphosphonates
  • Parathyroid Hormone-Related Protein
  • Teriparatide
  • abaloparatide