Dual JAK1 and STAT3 mutations in a breast implant-associated anaplastic large cell lymphoma

Virchows Arch. 2018 Oct;473(4):505-511. doi: 10.1007/s00428-018-2352-y. Epub 2018 Apr 10.

Authors

Audrey Letourneau¹, Marie Maerevoet², Dina Milowich¹, Roland Dewind³, Bettina Bisig¹, Edoardo Missiaglia¹, Laurence de Leval⁴

Affiliations

¹ Institute of Pathology, Lausanne University Hospital (CHUV), Lausanne, Switzerland.
² Department of Haematology, Institut Jules Bordet, Brussels, Belgium.
³ Department of Pathology, Institut Jules Bordet, Brussels, Belgium.
⁴ Institute of Pathology, Lausanne University Hospital (CHUV), Lausanne, Switzerland. Laurence.deLeval@chuv.ch.

PMID: 29637270
DOI: 10.1007/s00428-018-2352-y

No abstract available

Publication types

Comparative Study

MeSH terms

Aged
Biomarkers, Tumor / analysis
Biomarkers, Tumor / genetics*
Breast Implantation / adverse effects*
Breast Implantation / instrumentation
Breast Implants / adverse effects*
Female
Humans
Immunohistochemistry
In Situ Hybridization, Fluorescence
Janus Kinase 1 / genetics*
Lymphoma, Large-Cell, Anaplastic / enzymology
Lymphoma, Large-Cell, Anaplastic / genetics*
Lymphoma, Large-Cell, Anaplastic / pathology
Lymphoma, Large-Cell, Anaplastic / therapy
Mutation*
Phosphorylation
Positron Emission Tomography Computed Tomography
STAT3 Transcription Factor / analysis
STAT3 Transcription Factor / genetics*

Substances

Biomarkers, Tumor
STAT3 Transcription Factor
STAT3 protein, human
JAK1 protein, human
Janus Kinase 1