Diagnostic challenges in a patient with an occult insulinoma:68 Ga-DOTA-exendin-4 PET/CT and 68Ga-DOTATATE PET/CT

Clin Case Rep. 2018 Mar 1;6(4):719-722. doi: 10.1002/ccr3.1448. eCollection 2018 Apr.

Abstract

Despite growing evidence for GLP-1R molecular-based imaging, successful localization of insulinomas may require the use of multiple imaging modalities. Not all benign insulinomas express the GLP-1R as expected. Our case demonstrates that there is a still an important role for traditional methods for the anatomical localization of an insulinoma.

Keywords: Islet cell; adenoma; diagnostic imaging; endocrine gland neoplasms; insulinoma; molecular imaging; nesidioblastosis; pancreatic neoplasms.

Publication types

  • Case Reports