Does the second messenger cAMP have a more complex role in controlling filamentous fungal morphology and metabolite production?

Microbiologyopen. 2018 Aug;7(4):e00627. doi: 10.1002/mbo3.627. Epub 2018 Apr 6.

Abstract

The effect of second messenger cAMP on the physiological aspects of fungal cells such as pigmentation has been reported previously. However, their actual role in the cellular biochemical cascade that eventually affects the fungal growth morphology, such as mycelial pellet formation, is unclear. This article intends to open up the detailed study on the possible correlative effect of cAMP on the morphological and physiological growth aspects of filamentous fungi, with special emphasis on the industrial metabolite production.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adenosine Triphosphate / metabolism
  • Cyclic AMP / metabolism*
  • Fungal Proteins / genetics
  • Fungal Proteins / metabolism
  • Fungi / genetics
  • Fungi / growth & development*
  • Fungi / metabolism*
  • Second Messenger Systems*

Substances

  • Fungal Proteins
  • Adenosine Triphosphate
  • Cyclic AMP