Abstract
In this Review, we consider the story of cocaine from its humble origins in South America to its status as one of the most abused substances in 21st century society. The synthesis and biosynthesis of cocaine are discussed, as well as its pharmacokinetics, metabolism, pharmacology, and importance in modern neuroscience and molecular imaging.
Keywords:
Alkaloids; Cocaine; Crack cocaine; Molecular imaging; Pablo Escobar; Stimulant.
Publication types
-
Historical Article
-
Research Support, N.I.H., Extramural
-
Review
MeSH terms
-
Cocaine / chemistry*
-
Cocaine / history*
-
Cocaine / pharmacology*
-
Crack Cocaine / chemistry
-
Crack Cocaine / history
-
Crack Cocaine / pharmacology
-
Dopamine Uptake Inhibitors / chemistry*
-
Dopamine Uptake Inhibitors / history*
-
Dopamine Uptake Inhibitors / pharmacology*
-
History, 19th Century
-
History, 20th Century
-
History, 21st Century
-
Humans
Substances
-
Crack Cocaine
-
Dopamine Uptake Inhibitors
-
Cocaine