The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension

John P Kinsella; Robin H Steinhorn; Mary P Mullen; Rachel K Hopper; Roberta L Keller; D Dunbar Ivy; Eric D Austin; Usha S Krishnan; Erika B Rosenzweig; Jeffrey R Fineman; Allen D Everett; Brian D Hanna; Tilman Humpl; J Usha Raj; Steven H Abman; Pediatric Pulmonary Hypertension Network (PPHNet)

doi:10.1016/j.jpeds.2018.02.040

The Left Ventricle in Congenital Diaphragmatic Hernia: Implications for the Management of Pulmonary Hypertension

J Pediatr. 2018 Jun:197:17-22. doi: 10.1016/j.jpeds.2018.02.040. Epub 2018 Apr 5.

Authors

John P Kinsella¹, Robin H Steinhorn², Mary P Mullen³, Rachel K Hopper⁴, Roberta L Keller⁵, D Dunbar Ivy⁶, Eric D Austin⁷, Usha S Krishnan⁸, Erika B Rosenzweig⁸, Jeffrey R Fineman⁹, Allen D Everett¹⁰, Brian D Hanna¹¹, Tilman Humpl¹², J Usha Raj¹³, Steven H Abman¹⁴; Pediatric Pulmonary Hypertension Network (PPHNet)

Affiliations

¹ Section of Neonatology, University of Colorado School of Medicine-Children's Hospital Colorado, Aurora, CO. Electronic address: john.kinsella@ucdenver.edu.
² Children's National Medical Center, George Washington University, Washington, DC.
³ Section of Cardiology, Boston Children's Hospital, Boston, MA.
⁴ Section of Pediatric Cardiology, Lucile Packard Children's Hospital Stanford, Palo Alto, CA.
⁵ Section of Neonatology, University of California-Benioff Children's Hospital, San Francisco, CA.
⁶ Section of Cardiology, University of Colorado School of Medicine-Children's Hospital Colorado, Aurora, CO.
⁷ Section of Pulmonary Medicine, Vanderbilt University Medical Center-Vanderbilt Children's Hospital, Nashville, TN.
⁸ Section of Pediatric Cardiology, Morgan Stanley Children's Hospital, Columbia University, New York, NY.
⁹ Section of Pediatric Critical Care, University of California-Benioff Children's Hospital, San Francisco, CA.
¹⁰ Section of Cardiology, Johns Hopkins University School of Medicine, Baltimore, MD.
¹¹ Division of Cardiology, Children's Hospital of Philadelphia Philadelphia, PA.
¹² Section of Cardiology, The Hospital for Sick Children-University of Toronto, Toronto, Ontario.
¹³ Section of Neonatology, University of Illinois-Chicago, Chicago, IL.
¹⁴ Section of Pulmonary Medicine, University of Colorado School of Medicine-Children's Hospital Colorado, Aurora, CO.

PMID: 29628412
DOI: 10.1016/j.jpeds.2018.02.040

No abstract available

Keywords: congenital diaphragmatic hernia; extracorporeal membrane oxygenation; milrinone; nitric oxide; patent ductus arteriosus; pulmonary hypoplasia.

Publication types

Research Support, N.I.H., Extramural
Review

MeSH terms

Echocardiography
Fetus
Heart Ventricles / physiopathology*
Hernias, Diaphragmatic, Congenital / complications*
Hernias, Diaphragmatic, Congenital / therapy
Humans
Hypertension, Pulmonary / etiology*
Hypertension, Pulmonary / therapy
Infant, Newborn
Ventricular Dysfunction, Left / etiology*
Ventricular Dysfunction, Left / therapy

Grants and funding

UL1 TR001082/TR/NCATS NIH HHS/United States