To Be Young at Heart

Patrick C H Hsieh; Timothy J Kamp

doi:10.1016/j.stem.2018.03.003

To Be Young at Heart

Cell Stem Cell. 2018 Apr 5;22(4):475-476. doi: 10.1016/j.stem.2018.03.003.

Authors

Patrick C H Hsieh¹, Timothy J Kamp²

Affiliations

¹ Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA; Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: phsieh@ibms.sinica.edu.tw.
² Department of Medicine, University of Wisconsin-Madison, Madison, WI, USA; Stem Cell and Regenerative Medicine Center, University of Wisconsin-Madison, Madison, WI, USA; Department of Cell and Regenerative Biology, University of Wisconsin-Madison, Madison, WI, USA. Electronic address: tjk@medicine.wisc.edu.

PMID: 29625063
DOI: 10.1016/j.stem.2018.03.003

Abstract

Recently in Cell, Mohamed et al. (2018) report a cell-cycle regulator gene cocktail identified from young cardiomyocytes that enables mouse, rat, and human cardiomyocyte proliferation and promotes heart regeneration after infarction, defying the non-dividing nature of adult mammalian cardiomyocytes and implying a new way to treat or prevent heart failure.

Publication types

Comment

MeSH terms

Animals
Cell Proliferation
Heart
Heart Failure*
Humans
Mice
Myocytes, Cardiac*
Rats
Regeneration