A novel null allele, HLA-DRB1*15:148N, identified in a Chinese family

HLA. 2018 Jun;91(6):544-545. doi: 10.1111/tan.13266.

Abstract

A single nucleotide deletion at position 187 of HLA-DRB1*15:01:01:01 results in a null allele, HLA-DRB1*15:148N.

Keywords: HLA-DRB1*15:148N; class II; null allele; sequence-based typing.

MeSH terms

  • Alleles
  • Asian People*
  • Bone Marrow Transplantation*
  • China
  • Family
  • Histocompatibility Testing
  • Humans
  • Leukemia / therapy*
  • Loss of Function Mutation / genetics*
  • Polymorphism, Genetic
  • Sequence Alignment
  • Transplant Recipients
  • World Health Organization