Optimizing the use of topical retinoids in Asian acne patients

J Dermatol. 2018 May;45(5):522-528. doi: 10.1111/1346-8138.14314. Epub 2018 Apr 3.

Abstract

Acne vulgaris is a common disease among people in Asia. International guidelines and treatment recommendations emphasize the central role of topical retinoids in the management of acne. However, topical retinoids remain underutilized in clinical practise, which may be in part due to fear of retinoid-associated dermatitis/lack of experience, particularly in Asian patients. There is a perception that Asian skin has a greater tendency toward sensitivity compared with Caucasian skin. In our clinical experience, topical retinoid therapy can be used with excellent effect to treat Asians with acne. This article discusses available published work regarding the use of topical retinoids in Asian populations, and presents tips for utilizing these important agents in daily practise. Optimizing use of topical retinoids may improve adherence and, in turn, therapeutic outcomes and patient satisfaction.

Keywords: acne vulgaris; irritation; racial skin; retinoids; tolerability.

Publication types

  • Review

MeSH terms

  • Acne Vulgaris / drug therapy*
  • Acne Vulgaris / ethnology
  • Administration, Cutaneous
  • Anti-Infective Agents / standards
  • Anti-Infective Agents / therapeutic use*
  • Asian People
  • Climate
  • Dermatologic Agents / standards
  • Dermatologic Agents / therapeutic use*
  • Drug Eruptions / etiology*
  • Drug Therapy, Combination / methods
  • Drug Therapy, Combination / standards
  • Humans
  • Medication Adherence
  • Patient Satisfaction
  • Practice Guidelines as Topic
  • Retinoids / standards
  • Retinoids / therapeutic use*
  • Severity of Illness Index
  • Skin / drug effects
  • Skin Pigmentation / physiology
  • Treatment Outcome

Substances

  • Anti-Infective Agents
  • Dermatologic Agents
  • Retinoids