The Use of Pyridostigmine in a Child With Chronic Intestinal Pseudo-Obstruction

Pediatrics. 2018 Apr;141(Suppl 5):S404-S407. doi: 10.1542/peds.2017-0007.

Abstract

Chronic intestinal pseudo-obstruction is a rare disorder that affects the motility of the gastrointestinal tract. It results in acute or subacute intestinal obstruction symptoms in the absence of mechanical lesion. It can lead to intestinal failure in children with significant strain on nutrition, growth, and development. There is no universally agreed protocol for management of chronic intestinal pseudo-obstruction in children, and there is wide variation in clinical practice.

Publication types

  • Case Reports

MeSH terms

  • Child
  • Cholinesterase Inhibitors / therapeutic use*
  • Chronic Disease
  • Female
  • Gastrointestinal Motility / drug effects
  • Humans
  • Intestinal Pseudo-Obstruction / complications
  • Intestinal Pseudo-Obstruction / drug therapy*
  • Intestinal Pseudo-Obstruction / physiopathology
  • Myotonic Dystrophy / complications
  • Pyridostigmine Bromide / therapeutic use*

Substances

  • Cholinesterase Inhibitors
  • Pyridostigmine Bromide