Poststreptococcal reactive arthritis in Japan

J Infect Chemother. 2018 Jul;24(7):531-537. doi: 10.1016/j.jiac.2018.02.012. Epub 2018 Mar 30.

Abstract

Reactive arthritis after Group A streptococcal infection (poststreptococcal reactive arthritis: PSRA) that does not meet the Jones criteria for acute rheumatic fever (ARF) has been reported as a new entity for over a decade. In Japan there are few reports of PSRA. We encountered four children with arthritis accompanied with Group A streptococcal infection in our department. We investigated our cases and the recent Japanese literature. Japanese cases of PSRA are frequently accompanied with uveitis and erythema nodosum, and tonsillectomy resolved their symptoms in some cases. There were overlap cases between ARF, juvenile idiopathic arthritis, and PSRA.

Keywords: Acute rheumatic fever; Anti-streptolysin O (ASLO); Carditis; Streptococcus pyogenes; Uveitis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / therapeutic use
  • Arthritis, Juvenile / diagnostic imaging*
  • Arthritis, Juvenile / microbiology
  • Arthritis, Reactive / diagnostic imaging*
  • Arthritis, Reactive / drug therapy
  • Arthritis, Reactive / microbiology*
  • Biomarkers / blood
  • Child
  • Child, Preschool
  • Drug Therapy, Combination
  • Erythema Nodosum
  • Female
  • Humans
  • Japan
  • Male
  • Rheumatic Fever / diagnostic imaging
  • Rheumatic Fever / microbiology
  • Streptococcal Infections / complications*
  • Streptococcal Infections / drug therapy
  • Tonsillectomy
  • Uveitis

Substances

  • Anti-Bacterial Agents
  • Biomarkers