Strong enhancement of the chemiluminescence of the Cu(II)-H2O2 system on addition of carbon nitride quantum dots, and its application to the detection of H2O2 and glucose

Tooba Hallaj; Mohammad Amjadi; Zhenlun Song; Robabeh Bagheri

doi:10.1007/s00604-017-2547-y

Strong enhancement of the chemiluminescence of the Cu(II)-H₂O₂ system on addition of carbon nitride quantum dots, and its application to the detection of H₂O₂ and glucose

Mikrochim Acta. 2017 Dec 19;185(1):67. doi: 10.1007/s00604-017-2547-y.

Authors

Tooba Hallaj¹, Mohammad Amjadi², Zhenlun Song³, Robabeh Bagheri³

Affiliations

¹ Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, 5166616471, Iran.
² Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, 5166616471, Iran. amjadi@tabrizu.ac.ir.
³ Surface Protection Research Group, Surface Department, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, 519 Zhuangshi Road, Ningbo, 315201, China.

PMID: 29594455
DOI: 10.1007/s00604-017-2547-y

Abstract

The authors report that carbon nitride quantum dots (CN QDs) exert a strong enhancing effect on the Cu(II)/H₂O₂ chemiluminescent system. Chemiluminescence (CL) intensity is enhanced by CN QDs by a factor of ~75, while other carbon nanomaterials have a much weaker effect. The possible mechanism of the effect was evaluated by recording fluorescence and CL spectra and by examining the effect of various radical scavengers. Emitting species was found to be excited-state CN QDs that produce green CL peaking at 515 nm. The new CL system was applied to the sensitive detection of H₂O₂ and glucose (via glucose oxidase-catalyzed formation of H₂O₂) with detection limits (3σ) of 10 nM for H₂O₂ and 100 nM for glucose. The probe was employed for glucose determination in human plasma samples with satisfactory results. Graphical abstract The effect of carbon nitride quantum dots (CN QDs) on Cu(II)-H₂O₂ chemiluminescence reaction was studied and the new CL system was applied for sensitive detection of glucose based on the glucose oxidase (GOx)-catalyzed formation of H₂O₂.

Keywords: Carbon nanomaterials; Fenton reaction; Nanotechnology; Sensing; TEM; XPS.