Relative biological effectiveness in proton beam therapy - Current knowledge and future challenges

Clin Transl Radiat Oncol. 2018 Feb 1:9:35-41. doi: 10.1016/j.ctro.2018.01.006. eCollection 2018 Feb.

Armin Lühr^{1

2

3

4}, Cläre von Neubeck^{1

2}, Mechthild Krause^{1

2

3

5

4}, Esther G C Troost^{1

2

3

5

4}

¹ OncoRay - National Center for Radiation Research in Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Helmholtz-Zentrum Dresden - Rossendorf, Dresden, Germany.
² German Cancer Consortium (DKTK), Partner Site Dresden, and German Cancer Research Center (DKFZ), Heidelberg, Germany.
³ Helmholtz-Zentrum Dresden - Rossendorf, Institute of Radiooncology - OncoRay, Dresden, Germany.
⁴ Department of Radiotherapy and Radiation Oncology, Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
⁵ National Center for Tumor Diseases (NCT), Partner Site Dresden, Germany; German Cancer Research Center (DKFZ), Heidelberg, Germany; Faculty of Medicine and University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany; Helmholtz Association/Helmholtz-Zentrum Dresden - Rossendorf (HZDR), Dresden, Germany.

No abstract available

Keywords: Clinical side-effects; Dose recalculation; In vitro and in vivo models; MRI; RBE; Relative biological effectiveness.

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