Spontaneous chordae tendineae rupture during peripartum

Am J Emerg Med. 2018 Jun;36(6):1127.e1-1127.e3. doi: 10.1016/j.ajem.2018.03.038. Epub 2018 Mar 19.

Abstract

Acute cardiopulmonary distress in pregnancy always carries exceptionally arduous challenge for physicians. Here we report a patient who sustained spontaneous chordae tendineae rupture complicated with severe mitral regurgitation and acute pulmonary edema during peripartum period. Probable causes of chordae tendineae rupture include mitral valve prolapse, infectious endocarditis, congenital heart disease, rheumatic heart disease, ischemic heart disease, connective tissue diseases, previous mitral valve surgery or pregnancy itself. The pathophysiology of spontaneous chordae tendineae rupture due to pregnancy remains unclear. However, certain physiological stress, including hormone changes related matrix remodeling, increased cardiac output during pregnancy or labor pain may precipitate to this condition. Literature reviews from previously reported cases showed that those who were diagnosed chordae tendineae rupture at very preterm period all had preterm delivery.

Keywords: Acute heart failure; Chordae tendineae rupture; Dyspnea; Pregnancy.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Chordae Tendineae / diagnostic imaging*
  • Chordae Tendineae / pathology
  • Diuretics / therapeutic use
  • Echocardiography, Doppler, Color
  • Female
  • Heart Valve Prosthesis Implantation
  • Humans
  • Mitral Valve Insufficiency / diagnostic imaging*
  • Mitral Valve Insufficiency / physiopathology
  • Peripartum Period*
  • Pregnancy
  • Pregnancy Complications, Cardiovascular / physiopathology*
  • Pulmonary Edema / diagnostic imaging*
  • Pulmonary Edema / physiopathology
  • Rupture, Spontaneous / complications
  • Rupture, Spontaneous / diagnostic imaging*
  • Rupture, Spontaneous / pathology
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Diuretics