Knowledge and behaviors in relation to antibiotic use among rural residents in Anhui, China

Pharmacoepidemiol Drug Saf. 2018 Jun;27(6):652-659. doi: 10.1002/pds.4429. Epub 2018 Mar 26.

Abstract

Objectives: To examine antibiotic-related knowledge and behaviors in rural Anhui, identify factors associated with knowledge, and explore the relationship between knowledge and antibiotic use.

Methods: Cross-sectional study of a random sample of 2760 residents of rural China using structured interviews.

Results: The response rate was 94.6%. A total of 2390 respondents (91.6%) believed that antibiotics can control viruses; 2007 (77.5%) respondents thought that a combination of antibiotics is more effective than a single class; and 590 (22.6%) were able to name at least one disbenefit of using antibiotics. Multivariate analysis revealed those with a higher educational level and younger age group had greater knowledge of antibiotics (OR 2.54 and 0.77, respectively). Self-medication was common with 1052 (out of 2274 responses, 46.3%) of participants use over the counter or leftover medicines for common infections. Greater knowledge was associated with buying drugs without prescription (aOR 2.02; 95% CI, 1.29-3.17) and using leftover medication (aOR 2.80; 95% CI, 1.55-5.06).

Conclusion: Knowledge about antibiotics was low and reported use high. Worryingly those with greater knowledge had less desirable behaviors that highlights the urgent need for multifaceted interventions to change behavior.

Keywords: antibiotics use; epidemiology; individual behavior; pharmacoepidemiology; social determinants.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Anti-Bacterial Agents / therapeutic use*
  • China
  • Cross-Sectional Studies
  • Drug Prescriptions
  • Educational Status
  • Female
  • Health Knowledge, Attitudes, Practice*
  • Humans
  • Male
  • Middle Aged
  • Patient Education as Topic
  • Rural Population / statistics & numerical data*
  • Self Medication / statistics & numerical data*
  • Surveys and Questionnaires / statistics & numerical data
  • Virus Diseases / drug therapy

Substances

  • Anti-Bacterial Agents