The influence of adherence to antipsychotics medication on the quality of life among patients with schizophrenia in Indonesia

Perspect Psychiatr Care. 2019 Apr;55(2):147-152. doi: 10.1111/ppc.12276. Epub 2018 Mar 26.

Abstract

Purpose: Investigating factors that can predict medication adherence and quality of life, as well as the influence of adherence to medication on the quality of life among patients with schizophrenia.

Design and methods: This study applies descriptive cross-sectional design. Participants were determined from outpatient clinic in a psychiatric hospital in Indonesia. Several questionnaires were used, including self-report, Glasgow Antipsychotics Side-effect Scale, drug attitude inventory and SQOL-18.

Findings: Side-effect factor (p < .05) could influence medication adherence. Residential area (p < .05) could significantly influence quality of life. There was also a correlation between medication adherence and quality of life (p < .05).

Practice implications: Findings suggest to put more emphasis on assessing medication side effects.

Keywords: medication adherence; patients with schizophrenia; quality of life.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use*
  • Cross-Sectional Studies
  • Female
  • Humans
  • Indonesia / epidemiology
  • Logistic Models
  • Male
  • Medication Adherence / statistics & numerical data*
  • Middle Aged
  • Psychiatric Status Rating Scales
  • Quality of Life*
  • Schizophrenia / drug therapy*
  • Schizophrenic Psychology
  • Self Report
  • Young Adult

Substances

  • Antipsychotic Agents