Pericentral hydroxychloroquine retinopathy in a Caucasian female

Nikhil Anand; Robert A Prinzi; Cory Hoeferlin; Jiong Yan; Nieraj Jain

doi:10.1016/j.ajoc.2018.01.019

Pericentral hydroxychloroquine retinopathy in a Caucasian female

Am J Ophthalmol Case Rep. 2018 Jan 13:9:93-95. doi: 10.1016/j.ajoc.2018.01.019. eCollection 2018 Mar.

Authors

Nikhil Anand¹, Robert A Prinzi¹, Cory Hoeferlin², Jiong Yan¹, Nieraj Jain¹

Affiliations

¹ Department of Ophthalmology, Emory University, Atlanta, GA, USA.
² Emory University School of Medicine, Atlanta, GA, USA.

Abstract

Purpose: To report a rare presentation of the pericentral pattern of hydroxychloroquine (HCQ) retinal toxicity in a Caucasian female.

Observations: The patient presented with 20 years of exposure to HCQ, at a daily dose of 5.2mg/kg of actual body weight, and manifested a pericentral-only phenotype of HCQ toxicity, as demonstrated with detailed structural and functional testing.

Conclusions and importance: Although rare, the pericentral pattern of HCQ toxicity may occur in Caucasian patients in the absence of paracentral changes.

Keywords: Bull's eye maculopathy; Hydroxychloroquine; Multifocal electroretinogram; Pericentral; Plaquenil; Toxicity.

Publication types

Case Reports