Abstract
A frameshift because of a two-nucleotide deletion results in an HLA-C null allele, HLA-C*02:135N.
Keywords:
Illumina Miseq; Pacific Biosciences; Sanger sequencing; frameshift mutation; next-generation sequencing; novel HLA-C null allele.
© 2018 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
MeSH terms
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Alleles
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Bone Marrow / physiology*
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Bone Marrow Transplantation
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Canada
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Genotype*
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HLA-C Antigens / genetics*
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Histocompatibility Testing
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Humans
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Loss of Function Mutation / genetics*
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Sequence Analysis, DNA
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Tissue Donors
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White People*
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World Health Organization
Substances
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HLA-C Antigens
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HLA-C*02 antigen