Whole-exome sequencing reveals acquisition of mutations leading to the onset of donor cell leukemia after hematopoietic transplantation: a model of leukemogenesis

Leukemia. 2018 Aug;32(8):1822-1826. doi: 10.1038/s41375-018-0042-z. Epub 2018 Feb 5.
No abstract available

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Biomarkers, Tumor / genetics*
  • Cell Transformation, Neoplastic
  • Exome Sequencing / methods*
  • Female
  • Graft vs Host Disease / diagnosis
  • Graft vs Host Disease / etiology
  • Hematopoietic Stem Cell Transplantation / adverse effects*
  • Humans
  • Leukemia / diagnosis*
  • Leukemia / etiology
  • Leukemia / genetics
  • Models, Biological
  • Mutation*
  • Prognosis
  • Tissue Donors*
  • Transplantation Conditioning / adverse effects*

Substances

  • Biomarkers, Tumor