Chronic immunosuppression in the mature patient

Clin Dermatol. 2018 Mar-Apr;36(2):255-263. doi: 10.1016/j.clindermatol.2017.10.017. Epub 2017 Oct 4.

Abstract

In the ever-aging population of the world, the field of geriatrics continues to grow in importance. As human beings age, the skin undergoes a unique array of changes that predispose it to a specific set of dermatoses, infections, and neoplasms. Some of these physiologic alterations are comparable to the changes that happen in immunosuppressed individuals. Given the importance of immunosuppressive medications in treatment of many common skin conditions, we have reviewed the current literature to assist the practicing clinician in using immunosuppressive medications in the geriatric population.

Publication types

  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Biological Products / adverse effects
  • Biological Products / therapeutic use*
  • Humans
  • Immunity, Cellular / drug effects
  • Immunosuppression Therapy / adverse effects*
  • Immunosuppressive Agents / adverse effects
  • Immunosuppressive Agents / therapeutic use*
  • Skin Aging / immunology*
  • Skin Diseases, Bacterial / etiology
  • Skin Diseases, Infectious / etiology*
  • Skin Neoplasms / etiology*

Substances

  • Biological Products
  • Immunosuppressive Agents