Design, fabrication and structural optimization of tubular carbon/Kevlar®/PMMA/graphene nanoplate composite for bone fixation prosthesis

Biomed Mater. 2018 May 2;13(4):045010. doi: 10.1088/1748-605X/aab8d6.

Abstract

The present work investigates the mechanical properties of tubular carbon/Kevlar® composite coated with poly(methyl methacrylate)/graphene nanoplates as used in the internal fixation of bones. Carbon fibers are good candidates for developing high-strength biomaterials and due to better stress transfer and electrical properties, they can enhance tissue formation. In order to improve carbon brittleness, ductile Kevlar® was added to the composite. The tubular carbon/Kevlar® composites have been prepared with tailorable braiding technology by changing the fiber pattern and angle in the composite structure and the number of composite layers. Fuzzy analyses are used for optimizing the tailorable parameters of 80 prepared samples and then mechanical properties of selected samples are discussed from the viewpoint of mechanical properties required for a bone fixation device. Experimental results showed that with optimizing braiding parameters the desired composite structure with mechanical properties close to bone properties could be produced. Results showed that carbon/Kevlar® braid's physical properties, fiber composite distribution and diameter uniformity resulted in matrix uniformity, which enhanced strength and modulus due to better ability for distributing stress on the composite. Finally, as graphene nanoplates demonstrated their potential properties to improve wound healing intended for bone replacement, so reinforcing the PMMA matrix with graphene nanoplates enhanced the composite quality, for use as an implant.

MeSH terms

  • Biocompatible Materials / chemistry
  • Bone Substitutes / chemistry*
  • Bone and Bones / pathology
  • Carbon / chemistry*
  • Fracture Fixation, Internal / instrumentation*
  • Fuzzy Logic
  • Graphite / chemistry*
  • Humans
  • Materials Testing
  • Metal Nanoparticles / chemistry*
  • Nanostructures / chemistry
  • Orthopedic Equipment
  • Polymethyl Methacrylate / chemistry*
  • Porosity
  • Stress, Mechanical
  • Tensile Strength
  • Weight-Bearing

Substances

  • Biocompatible Materials
  • Bone Substitutes
  • Carbon
  • Graphite
  • Polymethyl Methacrylate