Comment on " Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis"

Mikhail Volkov; Jacqueline Dekkers; Bruno G Loos; Sergio Bizzarro; Thomas W J Huizinga; Helle A Praetorius; René E M Toes; Diane van der Woude

doi:10.1126/scitranslmed.aan8349

Comment on " Aggregatibacter actinomycetemcomitans-induced hypercitrullination links periodontal infection to autoimmunity in rheumatoid arthritis"

Sci Transl Med. 2018 Mar 21;10(433):eaan8349. doi: 10.1126/scitranslmed.aan8349.

Authors

Mikhail Volkov¹, Jacqueline Dekkers¹, Bruno G Loos², Sergio Bizzarro², Thomas W J Huizinga¹, Helle A Praetorius³, René E M Toes¹, Diane van der Woude⁴

Affiliations

¹ Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, Netherlands.
² Department of Periodontology, Academic Centre for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit, 1081 HV Amsterdam, Netherlands.
³ Department of Biomedicine, Aarhus University, Aarhus 8000, Denmark.
⁴ Department of Rheumatology, Leiden University Medical Center, 2333 ZA Leiden, Netherlands. dvanderwoude@lumc.nl.

PMID: 29563322
DOI: 10.1126/scitranslmed.aan8349

Abstract

The link between rheumatoid arthritis and exposure to a bacterial toxin was not found in a population of rheumatoid arthritis patients from Netherlands.

Publication types

Research Support, Non-U.S. Gov't
Comment

MeSH terms

Aggregatibacter actinomycetemcomitans
Arthritis, Rheumatoid*
Autoimmunity
Humans
Netherlands
Periodontitis*