Making sense of early high-dose intravenous vitamin C in ischemia/reperfusion injury

Angelique M E Spoelstra-de Man; Paul W G Elbers; Heleen M Oudemans-van Straaten

doi:10.1186/s13054-018-1996-y

Making sense of early high-dose intravenous vitamin C in ischemia/reperfusion injury

Crit Care. 2018 Mar 20;22(1):70. doi: 10.1186/s13054-018-1996-y.

Authors

Angelique M E Spoelstra-de Man¹, Paul W G Elbers², Heleen M Oudemans-van Straaten²

Affiliations

¹ VU University Medical Center Amsterdam, Department of Intensive Care Medicine, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands. am.spoelstra@vumc.nl.
² VU University Medical Center Amsterdam, Department of Intensive Care Medicine, Amsterdam Cardiovascular Sciences, Amsterdam Infection and Immunity Institute, Amsterdam, Netherlands.

Abstract

This article is one of ten reviews selected from the Annual Update in Intensive Care and Emergency Medicine 2018. Other selected articles can be found online at https://www.biomedcentral.com/collections/annualupdate2018 . Further information about the Annual Update in Intensive Care and Emergency Medicine is available from http://www.springer.com/series/8901 .

Publication types

Review

MeSH terms

Acute Coronary Syndrome / complications
Acute Coronary Syndrome / drug therapy
Administration, Intravenous
Ascorbic Acid / pharmacokinetics*
Ascorbic Acid / therapeutic use
Ascorbic Acid Deficiency / drug therapy
Ascorbic Acid Deficiency / etiology
Humans
Reperfusion Injury / drug therapy*
Reperfusion Injury / physiopathology
Reperfusion Injury / prevention & control
Time Factors*
Vitamins / pharmacokinetics
Vitamins / therapeutic use

Substances

Vitamins
Ascorbic Acid