Purpose of review: Chronic pain is a highly prevalent condition affecting millions of individuals.
Recent findings: In recent years, newer treatments have emerged that are changing the way clinicians treat pain pathogenesis, including novel nonopioid strategies. In this regard, spinal cord stimulation, the MILD procedure, and regenerative medicine have shown promise. This review summarizes recent literature on these three emerging treatment strategies. The results of this review suggest that under certain conditions, spinal cord stimulation, the MILD procedure, and regenerative medicine can be effective treatment modalities.
Keywords: Ligamentum flavum hypertrophy; Lumbar stenosis; MILD procedure; Pain; Regenerative medicine; Spinal cord stimulation.