Isolated splenic metastases from squamous cell carcinoma (SCC) of the cervix are rare, with few cases reported in the literature. We review here the main clinical and pathological findings in these patients, with emphasis on histopathological features. Because they are so rare, complex follow-up protocols for patients diagnosed with cervical SCC should exist because, if detected and treated, solitary splenic metastases seem to have a better prognosis than splenic metastases as part of a disseminated disease.