Cytogenetics data in adult men involved in the recycling of electronic wastes

Yanan Du; Yan Wang; Liqing Du; Chang Xu; Kaihua Ji; Jinhan Wang; Qiang Liu

doi:10.1016/j.dib.2018.02.051

Cytogenetics data in adult men involved in the recycling of electronic wastes

Data Brief. 2018 Feb 23:17:1405-1416. doi: 10.1016/j.dib.2018.02.051. eCollection 2018 Apr.

Authors

Yanan Du¹, Yan Wang¹, Liqing Du¹, Chang Xu¹, Kaihua Ji¹, Jinhan Wang¹, Qiang Liu¹

Affiliation

¹ Institute of Radiation Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin Key Laboratory of Molecular Nuclear Medicine, Tianjin, China.

Abstract

In this data article, 146 villagers (exposed group) were randomly selected from the workers who involved in the e-wastes recycling directly as a daily job in Tianjin. Control group, including 121 villagers, came from another town without e-waste disposal sites. Chromosomal aberrations (CA) and cytokinesis blocking micronucleus (CBMN) were performed to detect the cytogenetic effect for each subject. DNA damage was detected using comet assay; the DNA percentage in the comet tail (TDNA%), tail moment (TM), and Olive tail moment (OTM) were recorded to describe DNA damage to lymphocytes and spermatozoa. Routine semen analysis, spermatozoa motility and morphology were analyzed. The RT²Profiler PCR array was used to measure levels of expression of 84 genes related to quality of DNA. It showed significant relationships between CA, CBMN, DNA damage and exposure time in exposure subjects. The alteration of sperm motility rate, abnormality rate and total sperm counts had association with exposure time and age.