Novel Biosensors for the Rapid Detection of Toxicants in Foods

Adv Food Nutr Res. 2018:84:57-102. doi: 10.1016/bs.afnr.2018.01.003. Epub 2018 Mar 7.

Abstract

The modern environmental and food analysis requires sensitive, accurate, and rapid methods. The growing field of biosensors represents an answer to this demand. Unfortunately, most biosensor systems have been tested only on distilled water or buffered solutions, although applications to real samples are increasingly appearing in recent years. In this context, biosensors for potential food applications continue to show advances in areas such as genetic modification of enzymes and microorganisms, improvement of recognition element immobilization, and sensor interfaces. This chapter investigates the progress in the development of biosensors for the rapid detection of food toxicants for online applications. Recent progress in nanotechnology has produced affordable, mass-produced devices, and to integrate these into components and systems (including portable ones) for mass market applications for food toxicants monitoring. Sensing includes chemical and microbiological food toxicants, such as toxins, insecticides, pesticides, herbicides, microorganisms, bacteria, viruses and other microorganisms, phenolic compounds, allergens, genetically modified foods, hormones, dioxins, etc. Therefore, the state of the art of recent advances and future targets in the development of biosensors for food monitoring is summarized as follows: biosensors for food analysis will be highly sensitive, selective, rapidly responding, real time, massively parallel, with no or minimum sample preparation, and platform suited to portable and handheld nanosensors for the rapid detection of food toxicants for online uses even by nonskilled personnel.

Keywords: Antibody based; Biosensors; Cell based; Electrochemical; Enzymatic; Food analysis; Food monitoring; Food toxicants; Molecularly imprinted polymers; Nanotechnology; Online applications; Optical.

MeSH terms

  • Biological Assay
  • Biosensing Techniques*
  • Electrochemical Techniques
  • Food Analysis / methods
  • Food Contamination / analysis*
  • Lab-On-A-Chip Devices
  • Microfluidic Analytical Techniques
  • Molecular Imprinting
  • Nanotechnology / instrumentation*
  • Nanotechnology / methods*