Classical Swine Fever Outbreak after Modified Live LOM Strain Vaccination in Naive Pigs, South Korea

Emerg Infect Dis. 2018 Apr;24(4):798-800. doi: 10.3201/eid2404.171319.

Abstract

We report classical swine fever outbreaks occurring in naive pig herds on Jeju Island, South Korea, after the introduction of the LOM vaccine strain. Two isolates from sick pigs had >99% identity with the vaccine stain. LOM strain does not appear safe; its use in the vaccine should be reconsidered.

Keywords: Jeju Island; LOM strain; South Korea; classical swine fever; classical swine fever virus; livestock; modified live vaccine; outbreak; pigs; residual virulence; vaccination; viruses.

Publication types

  • Letter
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Classical Swine Fever / epidemiology*
  • Classical Swine Fever / pathology
  • Classical Swine Fever / prevention & control
  • Classical Swine Fever / virology*
  • Classical Swine Fever Virus* / classification
  • Classical Swine Fever Virus* / immunology
  • Disease Outbreaks*
  • Republic of Korea / epidemiology
  • Swine
  • Vaccination
  • Viral Vaccines / immunology

Substances

  • Viral Vaccines