Efficacy of Glutaraldehyde-Treated Leaflets for Mitral Valve Repair to Treat Active Infective Endocarditis: A Case Report

Susumu Isoda; Ichiya Yamazaki; Yusuke Matsuki; Hiroto Tomita; Yoshimi Yano; Toshikazu Gondo; Munetaka Masuda

doi:10.5761/atcs.cr.17-00222

Efficacy of Glutaraldehyde-Treated Leaflets for Mitral Valve Repair to Treat Active Infective Endocarditis: A Case Report

Ann Thorac Cardiovasc Surg. 2019 Dec 20;25(6):340-343. doi: 10.5761/atcs.cr.17-00222. Epub 2018 Mar 16.

Authors

Susumu Isoda¹, Ichiya Yamazaki¹, Yusuke Matsuki¹, Hiroto Tomita¹, Yoshimi Yano², Toshikazu Gondo³, Munetaka Masuda⁴

Affiliations

¹ Department of Cardiovascular Surgery, Fujisawa City Hospital, Fujisawa, Kanagawa, Japan.
² Yano Heart Clinic, Fujisawa, Kanagawa, Japan.
³ Department of Pathology, Fujisawa City Hospital, Fujisawa, Kanagawa, Japan.
⁴ Department of Surgery, Yokohama City University, Yokohama, Kanagawa, Japan.

Abstract

We report the use of glutaraldehyde (GA) in a case of valve repair for mitral valve prolapse associated with active infective endocarditis. GA scrubbed at the site of infection decontaminates and reinforces infected fragile tissue, avoids excessive debridement, and strengthens the edges of valve leaflets to facilitate suturing.

Keywords: active infective endocarditis; glutaraldehyde; mitral valve; valve repair.

Publication types

Case Reports

MeSH terms

Endocarditis, Bacterial / complications
Endocarditis, Bacterial / microbiology
Endocarditis, Bacterial / surgery*
Fixatives*
Glutaral / therapeutic use*
Humans
Mitral Valve / microbiology
Mitral Valve / surgery*
Mitral Valve Annuloplasty*
Mitral Valve Prolapse / microbiology
Mitral Valve Prolapse / surgery*
Streptococcal Infections / complications
Streptococcal Infections / microbiology
Streptococcal Infections / surgery*
Streptococcus / isolation & purification*
Suture Techniques*
Treatment Outcome

Substances

Fixatives
Glutaral

Supplementary concepts

Streptococcus parasanguinis