Coxiella burnetii endocarditis on bioprosthetic aortic valve, with peripheral arterial embolism

Cardiovasc Pathol. 2018 May-Jun:34:38-39. doi: 10.1016/j.carpath.2018.02.001. Epub 2018 Feb 16.

Abstract

Acute limb ischemia related to Coxiella burnetii endocarditis is rare. We report an original case of a 68-year-old man hospitalized for recurrent acute left limb ischemia in a context of atrial flutter, which revealed C. burnetii endocarditis. This case illustrates that even if embolic events are uncommon, septic embolisms must be systematically searched for in case of C. burnetii endocarditis. Conversely, extensive etiologic explorations must be performed in case of systemic embolism. New molecular techniques represent a major step forward in infective endocarditis diagnosis. Finally, diagnosis must be suspected in case of unexplained fever, inflammatory syndrome, or embolic event, especially in patients at risk. Conversely, in case of chronic Q fever, an immunodeficiency cause must be researched.

Keywords: Acute limb ischemia; Coxiella burnetii; Endocarditis; Q fever.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use
  • Aortic Valve / microbiology
  • Aortic Valve / pathology
  • Aortic Valve / surgery*
  • Aortic Valve Stenosis / surgery*
  • Bioprosthesis / adverse effects*
  • Biopsy
  • Coxiella burnetii / isolation & purification*
  • Device Removal
  • Echocardiography, Transesophageal
  • Embolism / diagnosis
  • Embolism / microbiology*
  • Embolism / therapy
  • Endocarditis, Bacterial / diagnosis
  • Endocarditis, Bacterial / microbiology*
  • Endocarditis, Bacterial / therapy
  • Heart Valve Prosthesis / adverse effects*
  • Heart Valve Prosthesis Implantation / adverse effects*
  • Heart Valve Prosthesis Implantation / instrumentation
  • Humans
  • Ischemia / diagnosis
  • Ischemia / microbiology*
  • Ischemia / therapy
  • Male
  • Peripheral Arterial Disease / diagnosis
  • Peripheral Arterial Disease / microbiology*
  • Peripheral Arterial Disease / therapy
  • Prosthesis-Related Infections / diagnosis
  • Prosthesis-Related Infections / microbiology*
  • Prosthesis-Related Infections / therapy
  • Q Fever / diagnosis
  • Q Fever / microbiology*
  • Q Fever / therapy
  • Recurrence
  • Thrombectomy

Substances

  • Anti-Bacterial Agents