Synchronous gallbladder squamous cell carcinoma and adenocarcinoma, both as primary tumors in one patient

Amir Vahedi; Mahzad Azimpouran; Ali Ghavidel; Mahsa Karbasi; Mehrdad Farhadi

doi:10.1016/j.ijscr.2018.02.039

Synchronous gallbladder squamous cell carcinoma and adenocarcinoma, both as primary tumors in one patient

Int J Surg Case Rep. 2018:45:1-3. doi: 10.1016/j.ijscr.2018.02.039. Epub 2018 Mar 6.

Authors

Amir Vahedi¹, Mahzad Azimpouran², Ali Ghavidel³, Mahsa Karbasi⁴, Mehrdad Farhadi⁵

Affiliations

¹ Department of General Pathology, Tabriz University of Medical Science, Tabriz, Iran. Electronic address: amirvahedy@gmail.com.
² Department of General Pathology, Tabriz University of Medical Science, Tabriz, Iran. Electronic address: mahzad.a.ma@gmail.com.
³ Liver and Gastrointestinal Diseases Research Centre, Tabriz University of Medical Sciences, Imam Reza Hospital, East Azerbaijan, Iran. Electronic address: ali.ghavidel3@gmail.com.
⁴ Department of Radiology, Tabriz University of Medical Science, Tabriz, Iran. Electronic address: mahsakrbsi@gmail.com.
⁵ Liver and Gastrointestinal Diseases Research Centre, Tabriz University of Medical Sciences, Imam Reza Hospital, East Azerbaijan, Iran. Electronic address: mehrdad_farhadi62@yahoo.com.

Abstract

Introduction: Synchronous primary carcinomas of gallbladder are extremely rare. In this paper, we report a case of double primary carcinomas in gallbladder CASE REPORT: A 65 year old male was admitted to the hospital for surgical removal of gallbladder, which was diagnosed as cholecystitis in ultrasonography. Macroscopic examination disclosed a single whitish mass in gallbladder neck and another distinct mass in the fundus as wall thickening. Pathologic findings revealed squamous cell carcinoma of the neck and adenocarcinoma in the fundus.

Discussion: This study represents an example of misdiagnosis. Being cautious is mandatory in order to manage the patient properly.

Conclusion: Synchronous primary carcinomas of gallbladder are rare. However this diagnosis should be taken into account in patients with cholecystitis features in order to seeking for the best surgical approach.

Keywords: Adenocarcinoma; Gallbladder cancer; Squamous cell carcinoma; Synchronous.