Range resolution and reproducibility of a dedicated phantom for proton PBS daily quality assurance

Z Med Phys. 2018 Dec;28(4):310-317. doi: 10.1016/j.zemedi.2018.02.001. Epub 2018 Mar 13.

Abstract

Purpose: Wedge phantoms coupled with a CCD camera are suggested as a simple means to improve the efficiency of quality assurance for pencil beam scanning (PBS) proton therapy, in particular to verify energy/range consistency on a daily basis. The method is based on the analysis of an integral image created by a pencil beam (PB) pattern delivered through a wedge. We have investigated the reproducibility of this method and its dependence on setup and positional beam errors for a commercially available phantom (Sphinx®, IBA Dosimetry) and CCD camera (Lynx®, IBA Dosimetry) system.

Material and methods: The phantom includes 4 wedges of different thickness, allowing verification of the range for 4 energies within one integral image. Each wedge was irradiated with a line pattern of clinical energies (120, 150, 180 and 230MeV). The equipment was aligned to the isocenter using lasers, and the delivery was repeated for 5 consecutive days, 4 times each day. Range was computed using the myQA software (IBA Dosimetry) and inter- and intra-setup uncertainty were calculated. Dependence of range on energy was investigated delivering the same pencil beam pattern but with energy variations in steps of ±0.2MeV for all the nominal energies, up to ±1.0MeV. Possible range uncertainties, caused by setup and positional errors, were then simulated including inclination of the phantom, pencil beam and couch shifts.

Results: Intra position setup (based on in-room laser system) shows a maximum in plane difference within 1.5mm. Range reproducibility (standard deviation) was less than 0.14mm. Setup and beam errors did not affect significantly the results, except for a vertical shift of 10mm which leads to an error in the range computation.

Conclusion: Taking into account different day-to-day setup and beam errors, day-to-day determination of range has been shown to be reproducible using the proposed system.

Keywords: Daily quality assurance; Dosimetry equipment; Pencil beam scanning; Range.

MeSH terms

  • Humans
  • Phantoms, Imaging
  • Quality Assurance, Health Care
  • Radiotherapy / instrumentation
  • Radiotherapy / standards*
  • Reproducibility of Results