Fulminant mucormycosis of maxillary sinuses after dental extraction inpatients with uncontrolled diabetic: Two case reports

J Mycol Med. 2018 Jun;28(2):399-402. doi: 10.1016/j.mycmed.2018.01.003. Epub 2018 Mar 13.
[Article in French]

Abstract

Mucormycosis is a rare but fulminant opportunistic fungal infection, which occurs most often in diabetic and immunocompromised patients. Dental extractions may create a portal of entry for the fungal infection. The mucormycosis may be the original cause of the pain and can be misdiagnosed as dental pain. In this paper, two cases of mucormycosis are reported after dental extractions and successfully treated with amphotericin B (case #1) and combined with posaconazole (case #2). The two cases we describe exemplify the fulminant mucormycosis of maxillary sinuses after dental extraction inpatients with uncontrolled diabetic support the findings that this predisposing condition created a suitable environment for the Mucorales growth. These case reports emphasize early recognition and urgent treatment of mucormycosis is necessary to prevent the spread of infection Therefore, dental surgeons and healthcare practitioners should become familiar with mucormycosis.

Keywords: Dental extraction; Diabetes; Maxilla; Mucormycosis.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use
  • Diabetes Complications / microbiology
  • Diabetes Mellitus / microbiology
  • Female
  • Humans
  • Immunocompromised Host
  • Male
  • Maxillary Sinus / microbiology*
  • Middle Aged
  • Mucorales / drug effects
  • Mucorales / isolation & purification*
  • Mucormycosis / diagnosis*
  • Mucormycosis / etiology
  • Opportunistic Infections / diagnosis
  • Opportunistic Infections / drug therapy
  • Sinusitis / diagnosis*
  • Sinusitis / drug therapy
  • Sinusitis / microbiology
  • Tooth Extraction / adverse effects*
  • Treatment Outcome
  • Triazoles / therapeutic use

Substances

  • Antifungal Agents
  • Triazoles
  • posaconazole
  • Amphotericin B