RUNX1 mutations in pediatric acute myeloid leukemia are associated with distinct genetic features and an inferior prognosis

Affiliations

• ¹ Department of Hematology/Oncology, Gunma Children's Medical Center, Gunma, Japan.
• ² Department of Pediatrics, Graduate School of Medicine, Gunma University, Gunma, Japan.
• ³ Clinical Research Center, National Hospital Organization Nagoya Medical Center, Aichi, Japan.
• ⁴ Department of Pediatrics, Yokohama City University Hospital, Kanagawa, Japan.
• ⁵ Department of Pathology and Tumor Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
• ⁶ Laboratory of DNA Information Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
• ⁷ Department of Pediatric Hematology and Oncology Research, National Research Institute for Child Health and Development, Tokyo, Japan.
• ⁸ Children's Cancer Center, National Center for Child Health and Development, Tokyo, Japan.
• ⁹ Department of Human Health Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
• ¹⁰ Department of Pediatrics, Shiga University of Medical Science, Shiga, Japan.
• ¹¹ Laboratory of Sequence Analysis, Human Genome Center, Institute of Medical Science, The University of Tokyo, Tokyo, Japan.
• ¹² Center for Hematology and Regenerative Medicine, Department of Medicine, Karolinska Institute, Stockholm, Sweden; and.
• ¹³ Japanese Red Cross Gunma Blood Center, Gunma, Japan.