Lumbar Osteophyte Avid on 68Ga-Prostate-Specific Membrane Antigen PET/CT

Clin Nucl Med. 2018 Jun;43(6):456-457. doi: 10.1097/RLU.0000000000002065.

Abstract

A 75-year-old man with recently diagnosed high-risk prostate cancer was referred for primary staging with Ga-prostate-specific membrane antigen (PSMA) PET/CT. The scan revealed intense Ga-PSMA uptake in a lumbar osteophyte on the right side of level L2/L3, whereas several other spinal osteophytes showed no Ga-PSMA uptake. MRI findings in the L3 vertebra was consistent with a benign Modic type 1 lesion, but MRI showed no signs of malignancy in the osteophyte with high Ga-PMSA uptake. This case presents an osteophyte as an addition to the list of potential benign pitfalls to be aware of when interpreting Ga-PSMA PET/CT.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Edetic Acid / analogs & derivatives*
  • Gallium Isotopes
  • Gallium Radioisotopes
  • Humans
  • Lumbar Vertebrae / diagnostic imaging*
  • Magnetic Resonance Imaging
  • Male
  • Oligopeptides*
  • Osteophyte / diagnostic imaging*
  • Positron Emission Tomography Computed Tomography*
  • Prostatic Neoplasms / diagnostic imaging*
  • Radiopharmaceuticals*

Substances

  • Gallium Isotopes
  • Gallium Radioisotopes
  • Oligopeptides
  • Radiopharmaceuticals
  • gallium 68 PSMA-11
  • Edetic Acid