Diagnostic performance of an optimized transcriptomic signature of risk of tuberculosis in cryopreserved peripheral blood mononuclear cells

Tuberculosis (Edinb). 2018 Jan:108:124-126. doi: 10.1016/j.tube.2017.11.001. Epub 2017 Nov 6.
No abstract available

Keywords: Biomarker; Correlate of risk; Diagnostic; PBMC; Whole blood; mRNA.

Publication types

  • Evaluation Study
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Area Under Curve
  • Case-Control Studies
  • Cryopreservation*
  • Gene Expression Profiling / methods*
  • Genetic Markers
  • High-Throughput Nucleotide Sequencing
  • Host-Pathogen Interactions
  • Humans
  • Leukocytes, Mononuclear / chemistry*
  • Leukocytes, Mononuclear / microbiology
  • Microfluidic Analytical Techniques
  • Mycobacterium tuberculosis / pathogenicity*
  • Predictive Value of Tests
  • RNA, Messenger / blood
  • RNA, Messenger / genetics*
  • ROC Curve
  • Reproducibility of Results
  • Reverse Transcriptase Polymerase Chain Reaction
  • Transcriptome*
  • Tuberculosis / blood
  • Tuberculosis / diagnosis*
  • Tuberculosis / genetics*
  • Tuberculosis / microbiology

Substances

  • Genetic Markers
  • RNA, Messenger