Oxidative responses and fungal infection biology

Semin Cell Dev Biol. 2019 May:89:34-46. doi: 10.1016/j.semcdb.2018.03.004. Epub 2018 Mar 12.

Abstract

The balance between reactive oxygen species and reactive nitrogen species production by the host and stress response by fungi is a key axis of the host-pathogen interaction. This review will describe emerging themes in fungal pathogenesis underpinning this axis.

Keywords: Fungal infection biology; Fungi; NADPH-oxidase; Oxidative stress; Reactive nitrogen species; Reactive oxygen species.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Fungi / immunology
  • Fungi / metabolism*
  • Fungi / pathogenicity
  • Host-Pathogen Interactions / immunology*
  • Humans
  • Mycoses / metabolism*
  • Mycoses / microbiology
  • Oxidative Stress / immunology*
  • Reactive Nitrogen Species / metabolism
  • Reactive Oxygen Species / metabolism

Substances

  • Reactive Nitrogen Species
  • Reactive Oxygen Species