Analysis of Outcomes of the Nutritional Status in Patients Qualified for Aortic Valve Replacement in Comparison to Healthy Elderly

Nutrients. 2018 Mar 5;10(3):304. doi: 10.3390/nu10030304.

Abstract

Severe aortic stenosis (AS) is associated with the reduction of muscle mass and may be associated with deterioration of nutritional status. Furthermore, malnourished cardiac patients are characterized by a higher risk of postoperative complications and mortality. The aim of this study was the evaluation and comparison of nutritional status, appetite and body composition in older people with severe aortic stenosis before aortic valve replacement and healthy elderly volunteers. One hundred and one patients, aged >65 years old with severe AS were included in the study. Nutritional status was assessed. Body composition was estimated using bioelectrical impedance analysis. Concentrations of albumin, prealbumin, triglycerides, total cholesterol and C-reactive protein were measured, and a complete blood count was done. About 40% of AS patients were at risk of malnutrition. They had decreased hand grip strength and they lost more body mass than the control group. Malnourished AS patients were older, had lower body mass indexes (BMIs) and lower aortic valve areas in comparison to well-nourished patients. Older AS patients, like their peers, show excessive body mass and, at the same time, the features of malnutrition. They have additional factors such as unintentional weight lost and decreased muscle strength which may be associated with worse outcomes.

Keywords: aortic stenosis; body composition; elderly; nutritional status.

MeSH terms

  • Age Factors
  • Aged
  • Aortic Valve Stenosis / blood
  • Aortic Valve Stenosis / diagnosis
  • Aortic Valve Stenosis / physiopathology
  • Aortic Valve Stenosis / surgery*
  • Appetite
  • Biomarkers / blood
  • Body Composition
  • Body Mass Index
  • Case-Control Studies
  • Electric Impedance
  • Female
  • Geriatric Assessment
  • Hand Strength
  • Healthy Aging*
  • Heart Valve Prosthesis Implantation*
  • Humans
  • Male
  • Malnutrition / blood
  • Malnutrition / diagnosis
  • Malnutrition / physiopathology*
  • Nutrition Assessment
  • Nutritional Status*
  • Risk Factors
  • Severity of Illness Index
  • Treatment Outcome

Substances

  • Biomarkers