Pneumonia in HIV-exposed and Infected Children and Association With Malnutrition

Pediatr Infect Dis J. 2018 Oct;37(10):1011-1013. doi: 10.1097/INF.0000000000001971.

Abstract

We evaluated the association between HIV exposed-uninfected (HEU) status, malnutrition and risk of death in Ugandan children hospitalized with pneumonia. Both HIV exposure and infection were associated with lower anthropometric indices on univariate analysis, and mid-upper arm circumference was significantly associated with overall mortality (odds ratio (OR), 0.96) in a multivariable model. HIV infection (OR 5.0) but not HEU status was associated with overall mortality. Malnutrition may contribute to poor pneumonia outcomes among HIV-infected and HEU children requiring hospitalization.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anthropometry
  • Child, Preschool
  • Data Analysis
  • HIV
  • HIV Infections / complications*
  • Hospitalization / statistics & numerical data
  • Humans
  • Infant
  • Malnutrition / complications*
  • Odds Ratio
  • Pneumonia / complications*
  • Pneumonia / mortality
  • Prospective Studies
  • Risk Factors
  • Uganda