Description of a Novel Set-up for Functional Echocardiographic Assessment of Left Ventricular Performance During Ex Vivo Heart Perfusion

Giulia Maria Ruggeri; Joshua Qua Hiansen; Emanuele Pivetta; Azad Mashari; Flavia Ballocca; Roberto Vanin Pinto Ribeiro; Liming Xin; Mitesh Badiwala; Babita Thampinathan; Massimiliano Meineri

doi:10.1213/ANE.0000000000002866

Description of a Novel Set-up for Functional Echocardiographic Assessment of Left Ventricular Performance During Ex Vivo Heart Perfusion

Anesth Analg. 2018 Sep;127(3):e36-e39. doi: 10.1213/ANE.0000000000002866.

Affiliations

¹ From the Department of Anesthesia and Pain Management, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
² Department of Epidemiology, University of Torino, Torino, Italy.
³ Division of Cardiovascular Surgery, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
⁴ Department of Mechanical & Industrial Engineering, University of Toronto, Toronto, Ontario, Canada.
⁵ Division of Cardiology, Toronto General Hospital, University Health Network, Toronto, Ontario, Canada.
⁶ Interdepartmental Division of Critical Care, University of Toronto, Toronto, Ontario, Canada.

PMID: 29505446
DOI: 10.1213/ANE.0000000000002866

Abstract

Ex vivo heart perfusion (EVHP) is a new technology aimed at decreasing cold ischemia time and evaluating cardiac function before transplanting a donor heart. In an experimental EVHP swine model, we tested a 3D-printed custom-made set-up to perform surface echocardiography on an isolated beating heart during left ventricular loading. The views obtained at any time point were equivalent to standard transesophageal and transthoracic views. A decrease in left ventricular function during EVHP was observed in all experiments.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Animals
Cardiopulmonary Bypass / methods*
Echocardiography, Transesophageal / methods*
Male
Printing, Three-Dimensional*
Swine
Ventricular Function, Left / physiology*