Obesity: Risk Factor for Increased Resource Utilization at Bidirectional Glenn

JPEN J Parenter Enteral Nutr. 2018 Jan;42(1):49-55. doi: 10.1002/jpen.1029. Epub 2017 Nov 3.

Abstract

Background: Underweight infants with single-ventricle cardiac physiology have been shown to have increased morbidity, mortality, and resource utilization. The purpose of this study was to determine whether patients who were overweight, as defined by weight-for-length z score >90th percentile, were similarly at risk for increased resource utilization, as defined by mechanical ventilation hours (VHs) and intensive care unit length of stay (ICU LOS).

Methods: We evaluated resource utilization for 109 patients from our institution who underwent bidirectional Glenn surgery from January 2010 to June 2015 and met prespecified inclusion criteria. Patients were divided into 3 groups: underweight (z score, <5th percentile), normal weight (z score, 5th-90th percentile), and overweight (z score, >90th percentile).

Results: ICU LOS was longer in the overweight group (median, 18.5 days) when compared with the under- and normal-weight groups (median LOS, 11 and 9 days, respectively) but did not reach statistical significance. VHs were also increased in the overweight group (median, 72 hours) when compared with the underweight (median, 27 hours) and normal weight (median, 25 hours) groups. This increase in VHs was statistically significant (P = .03).

Conclusions: This study suggests that patients with single-ventricle physiology who are overweight at the time of their bidirectional Glenn surgery may be at risk for increased resource utilization as compared with those who meet or fail to meet their caloric recommendations. These findings represent an underappreciated risk factor in this already-vulnerable patient population, providing potential opportunity for intervention and improved outcomes.

Keywords: cardiac disease; critical care; life cycle; obesity; pediatrics; research and diseases; surgery.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Cohort Studies
  • Female
  • Fontan Procedure / economics*
  • Health Resources / statistics & numerical data*
  • Humans
  • Infant
  • Intensive Care Units / statistics & numerical data
  • Length of Stay / statistics & numerical data
  • Male
  • Obesity / economics*
  • Respiration, Artificial / statistics & numerical data
  • Retrospective Studies
  • Risk Factors