Effect of the DASH-diet and salt Kardisal® on blood pressure in adolescents with prehypertension (Cooperative multicentre interventional study)

Neuro Endocrinol Lett. 2018 Feb;38(8):544-548.

Abstract

Background: In a cooperative multi-center interventional study of 60 probands with prehypertension and normal BMIs were followed for 3 months.

Design: The intervention included the DASH diet for 3 months in 30 probands plus sodium limited intake using the low sodium salt Kardisal® (60% NaCl, 40% KCl) (group A) and the DASH diet for 3 months in 30 probands without Kardisal® (group B).

Results: In group A (n=26 probands evaluated) the systolic blood pressure (median) decreased significantly from 138 to 129 mmHg (p<0.001), while the diastolic blood pressure had a statistically non-significant decrease. In group B (n=25 probands evaluated) the SBP decreased significantly from 135 to 132 mmHg (p<0.001), and the DBP decreased significantly from 85 to 69 mmHg (p<0.001).

Conclusion: Despite a relatively short period on the DASH diet, the intervention produced a significant decrease in the blood pressure of prehypertensive adolescents. The additional use of a low sodium salt for home cooking was not found to have any advantages over the DASH diet alone.

Publication types

  • Clinical Trial
  • Multicenter Study

MeSH terms

  • Adolescent
  • Adult
  • Blood Pressure Monitoring, Ambulatory
  • Blood Pressure*
  • Diet, Sodium-Restricted*
  • Dietary Approaches To Stop Hypertension*
  • Female
  • Humans
  • Male
  • Pilot Projects
  • Prehypertension / diet therapy*
  • Prehypertension / physiopathology*
  • Young Adult