Generation of fluorescently labeled tracers - which features influence the translational potential?

EJNMMI Radiopharm Chem. 2017;2(1):15. doi: 10.1186/s41181-017-0034-8. Epub 2017 Dec 15.

Abstract

Given the increasing exploration of fluorescent tracers in the field of nuclear medicine, a need has risen for practical development guidelines that can help improve the translation aspects of fluorescent tracers. This editorial discusses the does and don'ts in developing fluorescence tracers. It has been put forward by the European Association of Nuclear Medicine (EANM) Translational Molecular Imaging & Therapy committee and has been approved by the EANM board.

Keywords: Dual-modality; Fluorescence; Image guided surgery; Molecular imaging; Nuclear medicine; Tracers.