The management of infected elbow arthroplasty by two-stage revision

J Shoulder Elbow Surg. 2018 May;27(5):879-886. doi: 10.1016/j.jse.2017.12.033. Epub 2018 Mar 1.

Abstract

Background: Deep prosthetic infection is a potentially devastating complication after total elbow arthroplasty, with an incidence of up to 12%. This study examined the demographics, microbiologic profile, and outcomes of infected total elbow arthroplasty treated with 2-stage revision in a tertiary referral unit.

Methods: We identified 19 consecutive patients (mean age, 65 years) undergoing revision arthroplasty for deep prosthetic infection. All patients underwent a first-stage procedure with removal of implants, débridement, and insertion of an antibiotic-loaded cement spacer, followed by at least 6 weeks of intravenous antibiotics. Fourteen patients required a second-stage revision.

Results: Five patients did not undergo a second-stage procedure because of patient choice (n = 2), medical or surgical risk factors (n = 2), and death from an unrelated cause (n = 1). Of the 19 patients undergoing a first-stage procedure, 16 (84%) remained infection free, and 11 of the 14 patients (79%) undergoing reimplantation of an elbow prosthesis remained infection free. Six patients required further surgery (3 for recurrent infection, 3 for noninfective indications). The commonest infecting organism was Staphylococcus aureus (47%). A degree of postoperative ulnar nerve dysfunction occurred in 37% of patients, but all resolved fully without further treatment.

Conclusions: Management of prosthetic joint infection using 2-stage revision can result in high rates of eradication, although rates of reoperation and transient ulnar nerve dysfunction are high.

Keywords: Elbow; arthroplasty; infection; periprosthetic; replacement; revision.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use*
  • Arthroplasty, Replacement, Elbow / adverse effects*
  • Debridement / methods*
  • Disease Management*
  • Elbow Prosthesis / microbiology*
  • Female
  • Humans
  • Male
  • Middle Aged
  • Prosthesis-Related Infections / microbiology
  • Prosthesis-Related Infections / therapy*
  • Reoperation
  • Staphylococcal Infections / microbiology
  • Staphylococcal Infections / therapy*
  • Staphylococcus aureus / isolation & purification
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents